Buenos Aires is Argentina’s big, cosmopolitan capital city. Its center is the Plaza de Mayo, lined with stately 19th-century buildings including Casa Rosada, the iconic, balconied presidential palace. Other major attractions include Teatro Colón, a grand 1908 opera house with nearly 2,500 seats, and the modern MALBA museum, displaying Latin American art.

Ushuaia is a resort town in Argentina. It's located on the Tierra del Fuego archipelago, the southernmost tip of South America, nicknamed the “End of the World.” The windswept town, perched on a steep hill, is surrounded by the Martial Mountains and the Beagle Channel. It's the gateway to Antarctica cruises and tours to nearby Isla Yécapasela, known as “Penguin Island” for its penguin colonies.

Ushuaia is a resort town in Argentina. It's located on the Tierra del Fuego archipelago, the southernmost tip of South America, nicknamed the “End of the World.” The windswept town, perched on a steep hill, is surrounded by the Martial Mountains and the Beagle Channel. It's the gateway to Antarctica cruises and tours to nearby Isla Yécapasela, known as “Penguin Island” for its penguin colonies.

Punta Arenas is a city near the tip of Chile's southernmost Patagonia region. Located on the Strait of Magellan, which connects the Atlantic and Pacific oceans, it's often used as base for excursions to the surrounding wilderness and Antarctica. The Plaza Muñoz Gamero has a memorial to explorer Ferdinand Magellan, and the Museo Nao Victoria features a replica of one of his galleons.

Puerto Chacabuco is a town in Patagonia, southern Chile, known as a jumping-off point for the Aysén fjords. To the northeast is Lake Los Palos, with views of snowy mountains. The forested Simpson River National Reserve, home to cougars, is southeast. The nearby town of Coyhaique has a craft market selling handmade items. Glacier-fed San Rafael Lagoon and the Northern Patagonian Ice Field are to the southwest

Valparaíso is a port city on Chile’s coast. It's known for its steep funiculars and colorful, clifftop homes. La Sebastiana, the quirky former residence of Chilean poet Pablo Neruda, is now a museum with far-reaching Pacific views. During the 19th century, an influx of European immigrants left their mark on the city’s architecture and cultural institutions, many of which congregate around downtown’s Plaza Sotomayor.

Iquique is a coastal city in northern Chile, to the west of the Atacama Desert. A prosperous saltpeter mining town in the 19th century, today it's a popular holiday destination with a tax-free port area, Pacific beaches and a seafront casino. In its historic district, an iconic 19th-century clock tower stands in Arturo Prat Square, the city's main plaza.

Lima, the capital of Peru, lies on the country's arid Pacific coast. Though its colonial center is preserved, it's a bustling metropolis and one of South America’s largest cities. It's home to the Museo Larco collection of pre-Columbian art and the Museo de la Nación, tracing the history of Peru’s ancient civilizations. The Plaza de Armas and the 16th-century cathedral are the heart of old Lima Centro

New York City comprises 5 boroughs sitting where the Hudson River meets the Atlantic Ocean. At its core is Manhattan, a densely populated borough that’s among the world’s major commercial, financial and cultural centers. Its iconic sites include skyscrapers such as the Empire State Building and sprawling Central Park. Broadway theater is staged in neon-lit Times Square.

Halifax, an Atlantic Ocean port in eastern Canada, is the provincial capital of Nova Scotia. A major business centre, it’s also known for its maritime history. The city’s dominated by the hilltop Citadel, a star-shaped fort completed in the 1850s. Waterfront warehouses known as the Historic Properties recall Halifax’s days as a trading hub for privateers, notably during the War of 1812

Halifax, an Atlantic Ocean port in eastern Canada, is the provincial capital of Nova Scotia. A major business centre, it’s also known for its maritime history. The city’s dominated by the hilltop Citadel, a star-shaped fort completed in the 1850s. Waterfront warehouses known as the Historic Properties recall Halifax’s days as a trading hub for privateers, notably during the War of 1812

Québec City sits on the Saint Lawrence River in Canada's mostly French-speaking Québec province. Dating to 1608, it has a fortified colonial core, Vieux-Québec and Place Royale, with stone buildings and narrow streets. This area is the site of the towering Château Frontenac Hotel and imposing Citadelle of Québec. The Petit Champlain district’s cobblestone streets are lined with bistros and boutiques.

Trois-Rivières is a city in the province of Quebec, Canada. The riverfront Boréalis museum traces the history of the local paper industry. Nearby, the Centre d’exposition Raymond-Lasnier displays contemporary art. Quebec Museum of Folk Culture explores the cultural life of the Québécois. Adjacent is the Old Prison, dating from 1822. The Forges du Saint-Maurice has artifacts from Canada’s first iron-working community.

Toronto, the capital of the province of Ontario, is a major Canadian city along Lake Ontario’s northwestern shore. It's a dynamic metropolis with a core of soaring skyscrapers, all dwarfed by the iconic, free-standing CN Tower. Toronto also has many green spaces, from the orderly oval of Queen’s Park to 400-acre High Park and its trails, sports facilities and zoo.

Toronto, the capital of the province of Ontario, is a major Canadian city along Lake Ontario’s northwestern shore. It's a dynamic metropolis with a core of soaring skyscrapers, all dwarfed by the iconic, free-standing CN Tower. Toronto also has many green spaces, from the orderly oval of Queen’s Park to 400-acre High Park and its trails, sports facilities and zoo.

Point Pelee National Park is a national park in Essex County in southwestern Ontario, Canada where it extends into Lake Erie. The word pelée is French for 'bald'. Point Pelee consists of a peninsula of land, mainly of marsh and woodland habitats, that tapers to a sharp point as it extends into Lake Erie.

Detroit is the largest city in the midwestern state of Michigan. Near Downtown, the neoclassical Detroit Institute of Arts is famed for the Detroit Industry Murals painted by Diego Rivera, and inspired by the city’s ties to the auto industry, giving it the nickname "Motor City." Detroit is also the birthplace of Motown Records, whose chart-topping history is on display at their original headquarters, Hitsville U.S.A

Alpena is the only city and county seat of Alpena County in the U.S. state of Michigan. The population was 10,483 at the 2010 census. After Traverse City, it is the second most populated city in the Northern Michigan region. The city is surrounded by Alpena Township, but the two are administered autonomously

Milwaukee is a city in the U.S. state of Wisconsin on Lake Michigan's western shore. It's known for its breweries, many of which offer tours chronicling its role in the beer industry. Overlooking the Menomonee River, the Harley-Davidson Museum displays classic motorcycles, including one of Elvis Presley’s. Nearby is the Milwaukee Public Museum, with its large-scale European Village and a recreation of old Milwaukee.

Milwaukee is a city in the U.S. state of Wisconsin on Lake Michigan's western shore. It's known for its breweries, many of which offer tours chronicling its role in the beer industry. Overlooking the Menomonee River, the Harley-Davidson Museum displays classic motorcycles, including one of Elvis Presley’s. Nearby is the Milwaukee Public Museum, with its large-scale European Village and a recreation of old Milwaukee.