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Browse cruise sailings matched to South America.
Results 2302 available
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Duration 15 nights |Date 4 Nov 2026
Ship Aria Amazon
Cabin options for 2 adults will be checked before booking.
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Duration 8 nights |Date 4 Nov 2026
Ship MS Santa Cruz II
Departure - Quito
Duration 11 nights |Date 4 Nov 2026
Ship MS Santa Cruz II
Departure - Quito
Duration 10 nights |Date 5 Nov 2026
Ship National Geographic Islander II
Departure - Lima, Peru
Duration 8 nights |Date 5 Nov 2026
Ship Delfin III
Departure - Lima, Peru
Duration 17 nights |Date 6 Nov 2026
Ship Viking Octantis
Departure - Fort Lauderdale
Duration 9 nights |Date 6 Nov 2026
Ship National Geographic Endeavour II
Departure - Guayaquil
Duration 15 nights |Date 6 Nov 2026
Ship National Geographic Endeavour II
Departure - Guayaquil
Duration 22 nights |Date 6 Nov 2026
Ship MS Fram
Departure - Santiago, Chile
Duration 22 nights |Date 6 Nov 2026
Ship shipid 5597
Departure - Buenos Aires
Duration 15 nights |Date 6 Nov 2026
Ship shipid 6873
Departure - Guayaquil
Duration 9 nights |Date 6 Nov 2026
Ship shipid 6873
Departure - Guayaquil
Duration 7 nights |Date 7 Nov 2026
Ship Grandeur of the Seas
Departure - Colon, Panama
Duration 25 nights |Date 7 Nov 2026
Ship MSC Virtuosa
Departure - Southampton
Duration 7 nights |Date 7 Nov 2026
Ship AmaMagdalena
Departure - Cartagena, Colombia
Duration 7 nights |Date 7 Nov 2026
Ship Silver Origin
Departure - San Cristobal Island, Galapagos Islands
Duration 6 nights |Date 7 Nov 2026
Ship Silver Endeavour
Departure - King George Island, South Shetland Islands
Duration 18 nights |Date 7 Nov 2026
Ship Silver Wind
Departure - Puerto Williams, Chile
Duration 25 nights |Date 7 Nov 2026
Ship MSC Virtuosa
Departure - Southampton
Duration 6 nights |Date 8 Nov 2026
Ship Grandeur of the Seas
Departure - Cartagena, Colombia
Duration 14 nights |Date 8 Nov 2026
Ship Costa Diadema
Departure - Lisbon
Duration 15 nights |Date 8 Nov 2026
Ship Costa Diadema
Departure - Lisbon
Duration 12 nights |Date 8 Nov 2026
Ship Nieuw Amsterdam
Departure - Fort Lauderdale
Duration 21 nights |Date 8 Nov 2026
Ship Nieuw Amsterdam
Departure - Fort Lauderdale
Search sailings by destination, cruise line, ship, departure port and guide price.
Compare ships, ports, dates and guide prices before you enquire.
Our team checks the final price, cabin options and availability before you book.
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Arrival - Baltra, Galapagos Islands
Cabin options for 2 adults will be checked before booking.
From
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Arrival - Baltra, Galapagos Islands
Cabin options for 2 adults will be checked before booking.
From
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Arrival - Quito
Cabin options for 2 adults will be checked before booking.
From
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Arrival - Lima, Peru
Cabin options for 2 adults will be checked before booking.
From
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Arrival - Valparaiso
Cabin options for 2 adults will be checked before booking.
From
£8,995
Arrival - Guayaquil
Cabin options for 2 adults will be checked before booking.
From
£13,453
Arrival - Cusco/Lima
Cabin options for 2 adults will be checked before booking.
From
£21,123
Arrival - Punta Arenas, Chile
Cabin options for 2 adults will be checked before booking.
From
£34,944
Arrival - Buenos Aires
Cabin options for 2 adults will be checked before booking.
From
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Arrival - Cusco/Lima
Cabin options for 2 adults will be checked before booking.
From
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Arrival - Guayaquil
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From
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Arrival - Colon, Panama
One-cabin options found up to 4 guests.
From
£825
Arrival - Santos, Brazil
One-cabin options found up to 6 guests.
From
£2,187
Arrival - Barranquilla, Colombia
Cabin options for 2 adults will be checked before booking.
From
£3,299
Arrival - San Cristobal Island, Galapagos Islands
Cabin options for 2 adults will be checked before booking.
From
£10,850
Arrival - King George Island, South Shetland Islands
Cabin options for 2 adults will be checked before booking.
From
£19,300
Arrival - Puerto Williams, Chile
Cabin options for 2 adults will be checked before booking.
From
£25,700
Arrival - Santos, Brazil
Cabin options for 2 adults will be checked before booking.
From
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Arrival - Colon, Panama
One-cabin options found up to 4 guests.
From
£819
Arrival - Rio de Janeiro
One-cabin options found up to 4 guests.
From
£1,526
Arrival - Santos, Brazil
One-cabin options found up to 4 guests.
From
£1,711
Arrival - Fort Lauderdale
Cabin options for 2 adults will be checked before booking.
From
£2,244
Arrival - Fort Lauderdale
Cabin options for 2 adults will be checked before booking.
From
£3,279
