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Panama Canal & Pacific Gems - Miami to Los Angeles

Regent Seven Seas Cruises · Seven Seas Grandeur

Depart

Dec 29, 2026

Return

Jan 14, 2027

Port

Miami, Florida

Nights

16 nights

Seven Seas Grandeur at sea

At a glance

Built
2021
Tonnage
55498
Cabins
373
Crew
548

For more than thirty years, we have delivered unrivaled experiences throughout the world. All the while, we have been listening to our guests, evolving our services and continually refining each element of the Regent experience. Embrace the freedom enjoyed through the most all-inclusive luxury experience on the Seven Seas aboard a ship that elevates the pinnacle of ocean cruising to new heights.

Ask our cruise specialists about cruise line loyalty benefits, status match options, drinks packages, gratuities and any current offers available on this sailing.

On board

Boutiques

Boutiques

BusinessCenter

BusinessCenter

Charteuse

Charteuse

CoffeeConnection

CoffeeConnection

CompassRose

CompassRose

FitnessCenter

FitnessCenter

JoggingTrack

JoggingTrack

LaVeranda

LaVeranda

ObservationLounge

ObservationLounge

PoolGrill

PoolGrill

Reception

Reception

SereneSpaWellness

SereneSpaWellness

TheCasino

TheCasino

Itinerary

Route map for Cruise from Miami, Florida to Los Angeles, CAMiamiLos AngelesGeorge Town, Cayman IslandsCartagena, ColombiaPuerto QuetzalAcapulcoCabo San Lucas
Day 1-17

Cruise from Miami, Florida to Los Angeles, CA

  1. Day 1MiamiDec 29, 2026 • Departs at: 5 pm

    Sunny Florida skies, year-round warmth and sunshine, a buzzing nightlife and a mix of cultures define this cosmopolitan city. Celebrity-drenched South Beach attracts people-watchers and the Art Deco District is the largest collection of Art Deco architecture in the world. Tropical style shopping experience's are readily available from Bal Harbor to Lincoln Road and Coconut Grove. Enjoy authentic Cuban cuisine and culture along Calle Ocho or travel back in time with a visit to the historic Venetian Pool. There is something for everyone in this city dubbed the "Gateway to the America's."

  2. Day 2At SeaDec 30, 2026
  3. Day 3George Town, Cayman IslandsDec 31, 2026 • Arrives at: 9 am • Departs at: 4 pm

    Christopher Columbus discovered the Cayman Islands in 1503 and named them Las Tortugas, because the only inhabitants found were turtles. By 1530, they were known as the Caymanas, meaning "crocodile" in Carib. Although Sir Francis Drake visited the islands in 1568, they did not come under British rule until 1670. The Caymanians are descendants of the English, Irish, Scottish and Welsh seamen who settled the islands and later intermarried with Jamaican immigrants.

  4. Day 4At SeaJan 1, 2027
  5. Day 5Cartagena, ColombiaJan 2, 2027 • Arrives at: 7 am • Departs at: 2 pm

    Take a scenic drive through the residential area of Manga, and admire the beautiful mansions built in Republican-style architecture at the end of the 19th century. Explore the Castillo San Felipe de Barajas, a fort that was once the most important military structure built in Latin America. Enjoy a boat ride to the Islas del Rosario, 26 coral islands located off the coast of Isla Barú, and continue to the island of San Martín de Pajarales to visit the aquarium. Enjoy a spectacular dolphin and shark show and other marine attractions there. Board the beautiful Spanish Galleon, a replica of a 17th-century sailing ship, for a cruise of the inner bay of Cartagena.

  6. Day 6Panama CanalJan 3, 2027 • Arrives at: 7 am • Departs at: 6 pm

    The Panama Canal is an artificial 82 km waterway in Panama that connects the Atlantic Ocean with the Pacific Ocean. The canal cuts across the Isthmus of Panama and is a conduit for maritime trade

  7. Day 7At SeaJan 4, 2027
  8. Day 8Puntarenas, Costa RicaJan 5, 2027 • Arrives at: 6 am • Departs at: 7 pm

    Puntarenas, which means "Sandy Point" in Spanish, is the capital and main city in the province Puntarenas, Costa Rica, at the Pacific coast. The oddly-shaped province has its largest section in the South, far from the capital. A mountainous country, Costa Rica ranges from sea level to peaks as high as 13,000 feet and a succession of white, sandy beaches follow one another along the Pacific Coast. The country was discovered by Christopher Columbus in 1502.

  9. Day 9At SeaJan 6, 2027
  10. Day 10Puerto QuetzalJan 7, 2027 • Arrives at: 7 am • Departs at: 7 pm

    Drive into the mountains to beautiful old Antigua, once the country's colonial capital, and discover its lovely bougainvilleadraped buildings and breathtaking views of emerald volcanoes. Travel to famed Lake Atitlan and step back in time as you encounter the indigenous people in all their finery still living along the lakeshore. Or better yet, fly to Flores and experience the magnificent and enigmatic Mayan temples and palaces of the Tikal complex, surrounded by jungle.

  11. Day 11At SeaJan 8, 2027
  12. Day 12AcapulcoJan 9, 2027 • Arrives at: 8 am • Departs at: 5 pm

    Acapulco, nicknamed "Pearl of the Pacific," is Mexico's most glamorous pacific resort. Located on a deep, semi-circular bay, Acapulco is located southwest of Mexico City. Few destinations can match its superb weather with an average of 360 days of sunshine per year and with temperatures comfortably in the 80s. Acapulco was important as a port city for Spanish galleons sailing between Spain and the Orient long before it was "discovered" as a vacation playground.

  13. Day 13At SeaJan 10, 2027
  14. Day 14Cabo San LucasJan 11, 2027 • Arrives at: 10 am • Departs at: 6 pm

    Twenty years ago Cabo San Lucas, at the southernmost tip of Baja, was little more than a fishing village occasionally visited by itinerant Californian surfers and sport fishermen with the means to sail in or fly down. In recent years, however, it has rapidly become the focal point of Los Cabos, the catch-all term for the beaches and resorts ringing the toe of the peninsula. Condos have sprung up, palms transplanted, water piped in and everything is kept pristine.

  15. Day 15At SeaJan 12, 2027
  16. Day 16San DiegoJan 13, 2027 • Departs at: 10 pm

    The focus of San Diego seems to be ever changing, and each change adds to the city’s complexity and attractiveness. The city began as a remote Spanish mission and later came to be dominated by navy and marine bases. More recently, San Diego has established itself as a leader in scientific research and as a near perfect place to live, retire, conduct business or visit as a tourist. Its year-round perfect climate also helps lure people to its historic attractions.

  17. Day 17Los AngelesJan 14, 2027 • Arrives at: 7 am

    After the Jesuits built a series of missions along the coast of Alta California, the Spaniards established a port in 1781 as a supply stop for their coastal shipping routes. With the arrival of the transcontinental railroad and the discovery of oil, people began to arrive in droves. In 1923 the much-photographed giant letters were erected on the hill, and the golden age of Hollywood was born. The scale of Los Angeles, 90 miles long by 50 miles wide, defies belief.

Miami, FloridaMiamiAt SeaGeorge Town, Cayman IslandsCartagena, ColombiaPanama CanalPuntarenas, Costa RicaPuerto QuetzalAcapulcoCabo San LucasSan DiegoLos AngelesLos Angeles, CA

Cabin options

Compare the cabin types and onboard features shown for this sailing. Final price and availability are confirmed by our team when you inquire.

15 cabin grades listed for this sailing.

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