Panama Canal & Pacific Gems - Miami to Los Angeles from Miami, Florida, 29 Dec 2026 (16 nights)


Cruise search
We are checking available sailings, ship details and guide prices for you.


Ask our cruise specialists about cruise line loyalty benefits, status match options, drinks packages, gratuities and any current offers available on this sailing.
Sail with confidence
We explain the relevant financial protection before you book.
Always here to help
When plans change, your cruise specialists are here to help.
Carefully selected cruises
From short breaks to big adventures, we help narrow down the right sailing.
Cruise summary
Gallery

Onboard spaces
1 of 13 onboard highlights
Your itinerary
Port descriptions and imagery are shown where available for each day or port.
Sunny Florida skies, year-round warmth and sunshine, a buzzing nightlife and a mix of cultures define this cosmopolitan city. Celebrity-drenched South Beach attracts people-watchers and the Art Deco District is the largest collection of Art Deco architecture in the world. Tropical style shopping experience's are readily available from Bal Harbor to Lincoln Road and Coconut Grove. Enjoy authentic Cuban cuisine and culture along Calle Ocho or travel back in time with a visit to the historic Venetian Pool. There is something for everyone in this city dubbed the "Gateway to the America's."
Christopher Columbus discovered the Cayman Islands in 1503 and named them Las Tortugas, because the only inhabitants found were turtles. By 1530, they were known as the Caymanas, meaning "crocodile" in Carib. Although Sir Francis Drake visited the islands in 1568, they did not come under British rule until 1670. The Caymanians are descendants of the English, Irish, Scottish and Welsh seamen who settled the islands and later intermarried with Jamaican immigrants.
Take a scenic drive through the residential area of Manga, and admire the beautiful mansions built in Republican-style architecture at the end of the 19th century. Explore the Castillo San Felipe de Barajas, a fort that was once the most important military structure built in Latin America. Enjoy a boat ride to the Islas del Rosario, 26 coral islands located off the coast of Isla Barú, and continue to the island of San Martín de Pajarales to visit the aquarium. Enjoy a spectacular dolphin and shark show and other marine attractions there. Board the beautiful Spanish Galleon, a replica of a 17th-century sailing ship, for a cruise of the inner bay of Cartagena.
The Panama Canal is an artificial 82 km waterway in Panama that connects the Atlantic Ocean with the Pacific Ocean. The canal cuts across the Isthmus of Panama and is a conduit for maritime trade
Puntarenas, which means "Sandy Point" in Spanish, is the capital and main city in the province Puntarenas, Costa Rica, at the Pacific coast. The oddly-shaped province has its largest section in the South, far from the capital. A mountainous country, Costa Rica ranges from sea level to peaks as high as 13,000 feet and a succession of white, sandy beaches follow one another along the Pacific Coast. The country was discovered by Christopher Columbus in 1502.
Drive into the mountains to beautiful old Antigua, once the country's colonial capital, and discover its lovely bougainvilleadraped buildings and breathtaking views of emerald volcanoes. Travel to famed Lake Atitlan and step back in time as you encounter the indigenous people in all their finery still living along the lakeshore. Or better yet, fly to Flores and experience the magnificent and enigmatic Mayan temples and palaces of the Tikal complex, surrounded by jungle.
Acapulco, nicknamed "Pearl of the Pacific," is Mexico's most glamorous pacific resort. Located on a deep, semi-circular bay, Acapulco is located southwest of Mexico City. Few destinations can match its superb weather with an average of 360 days of sunshine per year and with temperatures comfortably in the 80s. Acapulco was important as a port city for Spanish galleons sailing between Spain and the Orient long before it was "discovered" as a vacation playground.
Twenty years ago Cabo San Lucas, at the southernmost tip of Baja, was little more than a fishing village occasionally visited by itinerant Californian surfers and sport fishermen with the means to sail in or fly down. In recent years, however, it has rapidly become the focal point of Los Cabos, the catch-all term for the beaches and resorts ringing the toe of the peninsula. Condos have sprung up, palms transplanted, water piped in and everything is kept pristine.
The focus of San Diego seems to be ever changing, and each change adds to the city’s complexity and attractiveness. The city began as a remote Spanish mission and later came to be dominated by navy and marine bases. More recently, San Diego has established itself as a leader in scientific research and as a near perfect place to live, retire, conduct business or visit as a tourist. Its year-round perfect climate also helps lure people to its historic attractions.
After the Jesuits built a series of missions along the coast of Alta California, the Spaniards established a port in 1781 as a supply stop for their coastal shipping routes. With the arrival of the transcontinental railroad and the discovery of oil, people began to arrive in droves. In 1923 the much-photographed giant letters were erected on the hill, and the golden age of Hollywood was born. The scale of Los Angeles, 90 miles long by 50 miles wide, defies belief.
What's included
Fare overview
This sailing is shown as a cruise-only guide fare with Regent Seven Seas Cruises. The fare is linked to the ship, itinerary and cabin category you choose. Drinks packages, gratuities, Wi-Fi, flights, transfers and shore experiences are only treated as included where they are confirmed before booking.

Sailing aboard
Seven Seas Grandeur
Your ship
For more than thirty years, we have delivered unrivaled experiences throughout the world. All the while, we have been listening to our guests, evolving our services and continually refining each element of the Regent experience. Embrace the freedom enjoyed through the most all-inclusive luxury experience on the Seven Seas aboard a ship that elevates the pinnacle of ocean cruising to new heights. Inspired by the past and stunningly reimagined for the future, Seven Seas Grandeur™ will exemplify our heritage of perfection with unrivaled space, unparalleled service, exceptional cuisine and transformative experiences that will begin the moment you step aboard.
Onboard facilities

Wellness/Spa
Deck plans
Explore the ship deck by deck. Deck plans can change and should be checked before booking.
Deck 10

These facilities are available aboard the ship. Their deck locations can be confirmed before booking.
Match cabin grade codes and colours to the selected deck plan.
Choose your cabin
Compare the cabin types and onboard features shown for this sailing. Final price and availability are confirmed before booking.
Next step
Continue to a separate page to review cruise extras and booking options around this sailing.
More sailings
Use horizontal scrolling, touch swipes, or the arrow keys to browse.
Important information
ATOL protected holidays
Where your booking includes flights, ATOL protection applies so your money and travel arrangements are financially protected.
Travel Trust Association
Book with confidence through a Travel Trust Association member, with customer money protected under approved trust arrangements.
Low deposit options
Secure selected sailings with flexible low deposit options, then spread the remaining balance before you travel.
Excellent customer service
Our cruise specialists are here before, during and after booking. Send an enquiry or call 0161 222 0822 for friendly support.
One Travel Club
Final price, cabin options and availability are checked before booking.
Clear price checks
Live prices and cabin options are checked before you continue.