Lisbon is Portugal’s hilly, coastal capital city. From imposing São Jorge Castle, the view encompasses the old city’s pastel-colored buildings, Tagus Estuary and Ponte 25 de Abril suspension bridge. Nearby, the National Azulejo Museum displays 5 centuries of decorative ceramic tiles. Just outside Lisbon is a string of Atlantic beaches, from Cascais to Estoril.

Lisbon is Portugal’s hilly, coastal capital city. From imposing São Jorge Castle, the view encompasses the old city’s pastel-colored buildings, Tagus Estuary and Ponte 25 de Abril suspension bridge. Nearby, the National Azulejo Museum displays 5 centuries of decorative ceramic tiles. Just outside Lisbon is a string of Atlantic beaches, from Cascais to Estoril.

Seville is the capital of southern Spain’s Andalusia region. It's famous for flamenco dancing, particularly in its Triana neighborhood. Major landmarks include the ornate Alcázar castle complex, built during the Moorish Almohad dynasty, and the 18th-century Plaza de Toros de la Maestranza bullring. The Gothic Seville Cathedral is the site of Christopher Columbus’s tomb and a minaret turned bell tower, the Giralda.

Málaga is a port city on southern Spain’s Costa del Sol, known for its high-rise hotels and resorts jutting up from yellow-sand beaches. Looming over that modern skyline are the city’s 2 massive hilltop citadels, the Alcazaba and ruined Gibralfaro, remnants of Moorish rule. The city's soaring Renaissance cathedral is nicknamed La Manquita ("one-armed lady") because one of its towers was curiously left unbuilt

Palma is a resort city and capital of the Spanish island of Mallorca (Majorca), in the western Mediterranean. The massive Santa María cathedral, a Gothic landmark begun in the 13th century, overlooks the Bay of Palma. The adjacent Almudaina is a Moorish-style Arab fortress converted to a royal residence. West of the city, hilltop Bellver Castle is a medieval fortress with a distinctive circular shape

Barcelona, the cosmopolitan capital of Spain’s Catalonia region, is known for its art and architecture. The fantastical Sagrada Família church and other modernist landmarks designed by Antoni Gaudí dot the city. Museu Picasso and Fundació Joan Miró feature modern art by their namesakes. City history museum MUHBA, includes several Roman archaeological sites.

Barcelona, the cosmopolitan capital of Spain’s Catalonia region, is known for its art and architecture. The fantastical Sagrada Família church and other modernist landmarks designed by Antoni Gaudí dot the city. Museu Picasso and Fundació Joan Miró feature modern art by their namesakes. City history museum MUHBA, includes several Roman archaeological sites.

Marseille, a port city in southern France, has been a crossroads of immigration and trade since its founding by the Greeks circa 600 B.C. At its heart is the Vieux-Port (Old Port), where fishmongers sell their catch along the boat-lined quay. Basilique Notre-Dame-de-la-Garde is a Romanesque-Byzantine church. Modern landmarks include Le Corbusier’s influential Cité Radieuse complex and Zaha Hadid’s CMA CGM Tower

The chic city of Monte Carlo in the petite kingdom of Monaco boasts some of the world’s most exclusive shopping and a beautiful old port. A fairy-tale aura has settled on this glittering city of the Grimaldi family, perhaps nowhere more elegantly than at the Prince’s Palace, where the late American actress-turned-princess Grace Kelly presided with Prince Rainier III. Monte Carlo’s medieval quarter perches on “The Rock,” an escarpment at the foot of the Maritime Alps, and offers spectacular views of the Mediterranean and the harbor lined with mega-yachts.

Florence, capital of Italy’s Tuscany region, is home to many masterpieces of Renaissance art and architecture. One of its most iconic sights is the Duomo, a cathedral with a terracotta-tiled dome engineered by Brunelleschi and a bell tower by Giotto. The Galleria dell'Accademia displays Michelangelo’s “David” sculpture. The Uffizi Gallery exhibits Botticelli’s “The Birth of Venus” and da Vinci’s “Annunciation.”

Florence, capital of Italy’s Tuscany region, is home to many masterpieces of Renaissance art and architecture. One of its most iconic sights is the Duomo, a cathedral with a terracotta-tiled dome engineered by Brunelleschi and a bell tower by Giotto. The Galleria dell'Accademia displays Michelangelo’s “David” sculpture. The Uffizi Gallery exhibits Botticelli’s “The Birth of Venus” and da Vinci’s “Annunciation.”

Rome is the capital city and a special comune of Italy, as well as the capital of the Lazio region. The city has been a major human settlement for almost three millennia. With 2,860,009 residents in 1,285 km², it is also the country's most populated comune.

Naples, a city in southern Italy, sits on the Bay of Naples. Nearby is Mount Vesuvius, the still-active volcano that destroyed nearby Roman town Pompeii. Dating to the 2nd millennium B.C., Naples has centuries of important art and architecture. The city's cathedral, the Duomo di San Gennaro, is filled with frescoes. Other major landmarks include the lavish Royal Palace and Castel Nuovo, a 13th-century castle

Sicily has been shaped by countless civilizations, from Greek to Byzantine to Roman. When it fell under Spain’s purview in the 17th century, it was celebrated as one of Europe’s ten great cities. Surrounded by undulating mountains, orange and olive groves and vineyards are plentiful. During World War II, Messina was the destination of the unofficial “Race to Messina” between US General Patton and British Field Marshall Montgomery. In the end, Patton arrived just hours before his British comrade, receiving credit for securing Sicily.

Crete, Greece's largest island, is known for its varied terrain, which ranges from fine-sand beaches at Elafonisi to the White Mountains. Mt. Ida, the tallest of the range, is home to the Ideon Cave, which was the birthplace of Zeus, according to Greek mythology. The capital, Heraklion, is home to the renowned Heraklion Archaeological Museum, housing Minoan artifacts, and Knossos, a Bronze Age settlement.

Ephesus is an ancient city in Turkey’s Central Aegean region, near modern-day Selçuk. Its excavated remains reflect centuries of history, from classical Greece to the Roman Empire – when it was the Mediterranean’s main commercial center – to the spread of Christianity. Paved streets wind past squares, baths and monumental ruins. The Temple of Hadrian was built before 138 A.D. for Emperor Hadrian’s visit

Athens is the capital of Greece. It was also at the heart of Ancient Greece, a powerful civilization and empire. The city is still dominated by 5th-century BC landmarks, including the Acropolis, a hilltop citadel topped with ancient buildings like the colonnaded Parthenon temple. The Acropolis Museum, along with the National Archaeological Museum, preserves sculptures, vases, jewelry and more from Ancient

Athens is the capital of Greece. It was also at the heart of Ancient Greece, a powerful civilization and empire. The city is still dominated by 5th-century BC landmarks, including the Acropolis, a hilltop citadel topped with ancient buildings like the colonnaded Parthenon temple. The Acropolis Museum, along with the National Archaeological Museum, preserves sculptures, vases, jewelry and more from Ancient

Athens is the capital of Greece. It was also at the heart of Ancient Greece, a powerful civilization and empire. The city is still dominated by 5th-century BC landmarks, including the Acropolis, a hilltop citadel topped with ancient buildings like the colonnaded Parthenon temple. The Acropolis Museum, along with the National Archaeological Museum, preserves sculptures, vases, jewelry and more from Ancient

Crete, Greece's largest island, is known for its varied terrain, which ranges from fine-sand beaches at Elafonisi to the White Mountains. Mt. Ida, the tallest of the range, is home to the Ideon Cave, which was the birthplace of Zeus, according to Greek mythology. The capital, Heraklion, is home to the renowned Heraklion Archaeological Museum, housing Minoan artifacts, and Knossos, a Bronze Age settlement.

Rhodes, the largest of Greece’s Dodecanese islands, is known for its beach resorts, ancient ruins and remnants of its occupation by the Knights of St. John during the Crusades. The city of Rhodes has an Old Town featuring the medieval Street of the Knights and the castlelike Palace of the Grand Masters. Captured by the Ottomans and then held by the Italians, the palace is now a history museum.

Ephesus is an ancient city in Turkey’s Central Aegean region, near modern-day Selçuk. Its excavated remains reflect centuries of history, from classical Greece to the Roman Empire – when it was the Mediterranean’s main commercial center – to the spread of Christianity. Paved streets wind past squares, baths and monumental ruins. The Temple of Hadrian was built before 138 A.D. for Emperor Hadrian’s visit

The Port of Istanbul is a passenger terminal for cruise liners, which is situated at Karaköy neighborhood of Beyoğlu district in Istanbul, Turkey

The Port of Istanbul is a passenger terminal for cruise liners, which is situated at Karaköy neighborhood of Beyoğlu district in Istanbul, Turkey