Your gateway to the Eternal City, Civitavecchia has served as Rome's seaport since the 13th century. The port has a long and venerable history. The emperor Trajan built a pleasure villa near the modern city, while Bernini and Michelangelo designed the harbor fortifications. Yet the Eternal City eternally beckons. The ancient capital of the Western World and the center of Christianity for nearly 2,000 years, Rome provides an inexhaustible feast. Visit the ruins of the Forum, view the splendors of the Sistine Chapel, or climb the Spanish Steps, once the heart of Rome's Bohemian Quarter. Rome has been a magnet luring the world's greatest artists, architects, and philosophers since the days of the Caesars.

Inhabited since antiquity, Salerno found its place as a Roman colony in 197 B.C. After the fall of Rome, a who's who of European kingdoms conquered the city including the Goths, the Byzantines and the Lombards. It's easy to see why. The warm Mediterranean sun and rolling hillsides beckon with new adventures and pinch-me-I must-be-dreaming experiences. Hike the jaw-dropping Mount Vesuvius, feel the centuries unfold as on a guided walk through the amazing cities of Pompeii and Herculaneum, or soak up the scenery with a cruise along the dazzling Amalfi Coast. Whatever you choose, Salerno offers precious memories that will last a lifetime.

Messina has played a major role in European history since its founding as a Greek colony in the 8th century B.C. During the Roman Empire, the city was a major port and commercial center, during the Middle Ages, Messina was the major port of departure for Crusaders. History has also left its scars: a massive earthquake leveled much of the city in 1908 and the World War II campaign for Sicily devastated Messina. Yet Messina emerged from that devastation with some of its historic treasures intact, including the 12th-century Annunziata dei Catalani Church. Messina is also your gateway to the rugged beauty of southeast Sicily, from the seaside resort of Taormina to Mt. Etna. Between the fall of Rome and the 1861 unification of Italy, the Arabs, the Normans, the Germans, the Spanish and the French ruled Sicily.

Palermo is a cultural feast, a fascinating combination of East and West, Arab and Norman that is quite unlike any other European city on the Mediterranean. A simple stroll can serve to illustrate Palermo's rich heritage. The Quattro Canti is the great square at the heart of the city. A short walk past its 17th-century palazzos and fountains brings the traveler to the Palazzo dei Normanni. Begun by Arab emirs in the 9th century, the Palazzo was finished by the island's Norman conquerors. The Palazzo's stone arches and buttresses stand in stark contrast to its Palatine Chapel. There elaborate tile work and mosaics lend mute testimonies to the Islamic and Byzantine influences that a lso shaped Palermo's culture. The city abounds in such colorful sights, from the neo-classical Teatro Massimo, one of the largest opera houses in Europe, to the catacombs beneath the Capuchin convent, where thousands of mummified bodies lie in eternal rest.

Malta is the largest in a group of seven islands that occupy a strategic position between Europe and Africa. The island's history is long and turbulent. Everyone from the Normans to the Nazis have vied for control of this small, honey-colored rock. For centuries the island was the possession of the knightly Order of St. John - the Knights Hospitaller. Valletta, Malta's current capital, was planned by the Order's Grandmaster Jean de la Valette to secure the island's eastern coast from Turk incursions. Founded in 1566, Valletta's bustling streets are lined with superb Baroque buildings and churches. Malta has a long history: the megalithic stone temples at Gozo may be the oldest freestanding structures on Earth. Malta has two official languages, Maltese (constitutionally the national language) and English. Malta was admitted to the European Union in 2004 and in 2008 became part of the eurozone.

Did the catastrophic volcanic eruption that ravaged Santorini circa 1600 B.C. destroy Crete's ancient Minoan civilization - and give birth to the myth of Atlantis? In 1967, archaeologists on Santorini unearthed the remains of a Bronze Age city that may have been home to as many as 30,000 people. Whether the Lost Continent of Atlantis is rooted in myth or reality, an undisputed fact remains. The eruption created a caldera - and one of the most dramatic land and seascapes in the entire Mediterranean. On Santorini, whitewashed buildings cling to vertiginous cliffs that plunge to a turquoise sea. Part of the Cyclades Archipelago, the three-island group of Santorini, Thirasia and uninhabited Aspronisi present the traveler with unforgettable vistas. The island has had a number of names throughout history - from Strongyle or "Round" to Thera in honor of an ancient hero. Santorini is more recent and stems from the island church dedicated to St. Irene - Santa Rini to foreign sailors.

Thanks to its proximity to the mainland, Mykonos was one of the first Greek islands to become an international travel destination. During the late '60s and early '70s, Mykonos was famed as a haunt for the rich. The island's nightlife - then and now - was a glittering whirl of colored lights, music, and parties. But there's another side to Mykonos - the neighboring island of Delos. In classical mythology, Delos was the birthplace of Apollo and his twin sister Artemis. Travelers to Delos can stroll among the island's vast ruins, which include three temples consecrated to the Sun God and the famed Lions Walk. Mykonos town features hip boutiques, restaurants, jewelry stores, souvenirs, taverns and cafés. The island's famed windmills are found just south of the waterfront.

From the port of Kusadasi on Turkey's Anatolian Coast, one travels into the past. Nearby stand the ruins of ancient Ephesus, a major site of archeological excavation. The city was once a Roman provincial capital and trading center. Ephesus is also home to several of Christendom's holiest sites. St. Paul preached at the Great Theater and the ruins of Ephesus' Basilica cover the tomb of Christ's most beloved disciple, St. John the Apostle. In Kusadasi, whitewashed stone houses rise in tiers behind the market district. The palm-lined esplanade is the center of town life, with thousands of merchants offering wares to rival the Grand Bazaar in Istanbul.

Archaeological evidence shows that Heraklion probably arose during the 9th century B.C. and was named in tribute to the Greek goddess Rhea, mother of Zeus. And like most Mediterranean cities, Heraklion has a long and turbulent history. Officially founded by the Saracens in the 9th century, the Byzantine Empire invaded in 961 only to lose control to the Crusaders who sold Crete to the Venetians in 1211 for a thousand silver coins. Heraklion finally flourished under the Venetians. Throughout the city you'll find stunning reminders of their influence: the Loggia, Venetian Walls, and Fountain of Morosini are just a few must-see examples. But Heraklion is probably best known as the gateway to the breathtaking 4,000 year-old Minoan ruins at Knossos and to the famous windmills stretched across the Lassithi Plateau.

The past maintains a vibrant presence in the cradle of Western civilization. Atop the Acropolis, the serene Parthenon sails above the commotion of the modern city. The tragedies of Aeschylus, Sophocles, and Euripides were performed in the Theater of Dionysus at the foot of the Acropolis. On Pnyx Hill, citizens of a fledgling democracy gathered to cast their votes on Athens' destiny. Then there is the hustle and bustle of the modern city, a metropolis of 4.5 million that spreads out from the foot of Mt. Lycabettus and across the plain. Packed with busy shops and lively tavernas, modern Athens is a colorful counterpoint to classical Greece. Piraeus is the port city for Athens and has been Athens' port of entry for over two millennia.