21 nights South America from Santos (Sao Paulo), 3 Apr 2027


Cruise search
We are checking available sailings, ship details and guide prices for you.


Ask our cruise specialists about cruise line loyalty benefits, status match options, drinks packages, gratuities and any current offers available on this sailing.
Sail with confidence
We explain the relevant financial protection before you book.
Always here to help
When plans change, your cruise specialists are here to help.
Carefully selected cruises
From short breaks to big adventures, we help narrow down the right sailing.
Cruise summary
Gallery

Dining
1 of 12 onboard highlights
Your itinerary
Port descriptions and imagery are shown where available for each day or port.
São Paulo, Brazil’s vibrant financial center, is among the world's most populous cities, with numerous cultural institutions and a rich architectural tradition. Its iconic buildings range from its neo-Gothic cathedral and the 1929 Martinelli skyscraper to modernist architect Oscar Niemeyer’s curvy Edifício Copan. The colonial-style Pátio do Colégio church marks where Jesuit priests founded the city in 1554.
As you’ll be able to appreciate when you cruise the Atlantic Ocean with MSC Cruises, in its position on the southern shore of the magnificent Guanabara Bay, Rio de Janeiro has, without a shadow of a doubt, one of the most stunning settings in the world. Extending for 20km along an alluvial strip, between an azure sea and forest-clad mountains, the city’s streets and buildings have been moulded around the foothills of the mountain range that provides its backdrop, while out in the bay there are many rocky islands fringed with white sand. The aerial views over Rio are breathtaking, and even the concrete skyscrapers that dominate the city’s skyline add to the attraction. As the former capital of Brazil and now its second-largest city, Rio has a remarkable architectural heritage, some of the country’s best museums and galleries, superb restaurants and a vibrant nightlife – in addition to its legendary beaches. A shore excursion on your MSC South America cruise can be the opportunity to vi…
On a peninsula north of Cabo Frio, Armação dos Búzios, or just Búzios, is an immensely scenic resort full of high-spending beautiful people, and a very popular port of call on holidays to Brazil with MSC Cruises. Armação, the main settlement, is built in a vaguely colonial style, its streets lined with restaurants, bars and chic boutiques, and has been nicknamed “Brazil’s St Tropez”. It comes then as little surprise to find that it was “discovered” by none other than Brigitte Bardot, who stumbled upon it while touring the area in 1964. Búzios consists of three main settlements, Manguinos, Armação and Ossos, each with its own distinct character. Manguinos, on the isthmus, is the main service centre, with a tourist office, a medical centre and banks. Midway along the peninsula, linked to Manguinos by a road lined with brash hotels, is Armação, an attractive village where cars are banned from some of the cobbled roads. Most of Búzio’s best restaurants and boutiques are concentrated here,…
High above the enormous bay of Todos os Santos (All Saints), where your MSC cruise ship awaits your return, Salvador de Bahia has an electric feel from the moment you arrive. This is the great cultural and historical centre of Brazil, where Afro-Brazilian heritage is strongest and where capoeira, candomblé and samba de roda were created. MSC South America cruises offer excursions to the centro histórico of this magical place, a melange of narrow cobbled streets, peeling purple walls, grand Baroque churches, kids kicking footballs, rastas, locals sipping bottled beer on plastic chairs, the wafting aroma of herbs and the almost constant beating of drums, especially as the sun sets. Beyond the old town Salvador is a vast, sprawling city, with a vibrant beach life, modern skyscrapers and plenty of favelas. The centro histórico is the traditional heart of Salvador; it’s built around the craggy, 70m-high bluff that dominates the eastern side of the bay, and is split into upper and lower sec…
On your South America cruise to Brazil, you’ll come across the big and burgeoning beach resort of Maceió, its striking beaches and clear, turquoise waters attracting cruisers from all over the world. It’s also smack in the middle of a far longer strip of some of the best beaches in the country, all easily accessible on day trips. When you arrive with your MSC cruise in Maceió, you’ll start off in the affluent and lively resort area that starts at Pajuçara, a few kilometres to the east of downtown, built along a spectacular beach. While the city centre itself, the commercial and administrative heart of the city just inland from a more polluted (and generally deserted) stretch of sand and the grubby port district, is somewhat down-at-heel it does have a smattering of belle époque buildings and enticing museums. However, what you’ll want to discover on your MSC South America cruise excursion is the amazing beaches. Sixteen kilometres south of Maceió, the coast road loops around Praia do…
Santa Cruz de Tenerife is the port capital of Tenerife, the largest of Spain’s seven Canary Islands. The city showcases incredible sights such as the Plaza de Espana, the church of St. Francis of Assisi, and the soaring white wave auditorium, the Auditorio de Tenerife. This quintessential Canary Island’s town is a colourful MSC Mediterranean Cruises destination where you can soak up the sun, dine in style, or take a dip in glittering waters.
Settled on the Strait of Gibraltar, Tangier, an MSC Mediterranean Cruises destination, is an energetic and multicultural port. This magical Moroccan city is distinguished by its whitewashed Medina, maze of evocative alleys, bustling squares, and fascinating people. Glimpse the Dar el Makhzen palace, the Church of Saint Andrew, Jardins de la Mendoubia park, and the famous Bab Al Fahs gate. Further afield, visit natural wonders including the surreal Caves of Hercules.
One of the busiest cruise ports in the Mediterranean, the seaside city of Barcelona is known for its iconic architecture, colourful culture, and world-class drinking and dining. Explore Antoni Gaudí’s surreal Sagrada Família, the famous boulevard of the Ramblas, the medieval Barri Gótic, and the Museu Picasso. But there’s even more to discover in this sprawling Spanish city, an MSC Mediterranean Cruises destination: from hidden tapas bars and fabulous food markets to Europe’s biggest football stadium.
TUNIS African and Arabic hospitality await you in exotic Tunis, on the coast of North Africa. Tunis, the capital of Tunisia, actually consists of three cities: the modern Capital City of the Tunisian Republic, with its wide streets, skyscrapers and busy sidewalk cafes; the Arabic Medina (Old Town) from the Middle Ages, an exciting labyrinth laden with secrets, narrow alleyways, small shops, huge mosques and palaces and finally Carthage, the ancient Phoenician - Roman city, which lies 18 km from the city
Naples is a large, sprawling Mediterranean port, with a centre that has many different focuses just waiting to be discovered on an MSC Mediterranean cruise excursion. MSC Mediterranean cruises also offer excursions to Pompeii. One of Campania’s most important Roman commercial centres – a moneyed resort for wealthy patricians and a trading town that exported wine and fish – the eruption of Mount Vesuvius in AD 79 in effect froze the town’s way of life as it stood at the time. Trips can also be taken to the island of Capri, place of legend, home to the mythical Sirens and a much-eulogized playground of the super-rich in the years since – though now it has settled down to a lucrative existence as a target for day-trippers from the mainland. Definitely worth a visit, but these days the origins of much of the purple prose may be hard to find.
What's included
Fare overview
This sailing is shown as a cruise-only guide fare with MSC Cruises. The fare is linked to the ship, itinerary and cabin category you choose. Drinks packages, gratuities, Wi-Fi, flights, transfers and shore experiences are only treated as included where they are confirmed before booking.

Sailing aboard
MSC Virtuosa
Your ship
MSC Virtuosa’s namesake comes from the word virtuoso, meaning someone highly skilled in any field of activity, and so MSC Virtuosa was named to pay homage to the skill and expertise of the MSC Cruises architects and shipyard partners at Les Chantiers de l’Atlantique who designed and built this innovative class of ships. This new cruise ship is one of the two largest in MSC Cruises’ fleet, along with her sister ship MSC Grandiosa, boasting an impressive array of guest features all coming together in perfect harmony to deliver the ultimate cruise holiday experience.
Onboard facilities

Bars/Lounges
Deck plans
Explore the ship deck by deck. Deck plans can change and should be checked before booking.
Deck 10 - Gershwin

These facilities are available aboard the ship. Their deck locations can be confirmed before booking.
Match cabin grade codes and colours to the selected deck plan.
Choose your cabin
Compare the cabin types and onboard features shown for this sailing. Final price and availability are confirmed before booking.
Use horizontal scrolling, trackpad gestures, touch swipes, or the arrow keys to browse cabin types.
Next step
Continue to a separate page to review cruise extras and booking options around this sailing.
More sailings
Use horizontal scrolling, touch swipes, or the arrow keys to browse.
Important information
ATOL protected holidays
Where your booking includes flights, ATOL protection applies so your money and travel arrangements are financially protected.
Travel Trust Association
Book with confidence through a Travel Trust Association member, with customer money protected under approved trust arrangements.
Low deposit options
Secure selected sailings with flexible low deposit options, then spread the remaining balance before you travel.
Excellent customer service
Our cruise specialists are here before, during and after booking. Send an enquiry or call 0161 222 0822 for friendly support.
One Travel Club
Final price, cabin options and availability are checked before booking.
Clear price checks
Live prices and cabin options are checked before you continue.