4 nights South Caribbean from Civitavecchia (Rome)
MSC Cruises · MSC Opera
Depart
Oct 29, 2026
Return
Nov 2, 2026
Port
Civitavecchia, Rome
Nights
4 nights

At a glance
- Built
- 2004
- Tonnage
- 65591
- Cabins
- 1071
- Crew
- 721
With its impressive array of new features and facilities, MSC Opera is now even better equipped to satisfy the needs of our guests. We’ve added spacious new cabins with balconies offering superb panoramic views and we have enlarged the restaurant and buffet areas to serve up an even greater variety of culinary treats.
Ask our cruise specialists about cruise line loyalty benefits, status match options, drinks packages, gratuities and any current offers available on this sailing.
On board

L'Approdo Restaurant

La Caravella Restaurant
Itinerary
Cruise from Civitavecchia, Rome to Barcelona
Day 1Civitavecchia (Rome), ItalyOct 29, 2026 • Departs at: 7 pm
Discover the culture and colour of Civitavecchia, an MSC Mediterranean Cruises destination. This Italian gem is an enjoyable flight from many European and non-European cities. Celebrated for its 16th-century Michelangelo Fort, ancient Taurine Baths, and marble Vanvitelli fountain, the port is a convenient starting point for visiting Rome, Italy’s regal and romantic capital.
Day 2Genoa (Portofino), ItalyOct 30, 2026 • Arrives at: 8 am • Departs at: 6 pm
Genoa is marvellously eclectic, vibrant and full of rough-edged style; it’s a great cruise excursion. Indeed “La Superba” (The Superb), as it was known at the height of its authority as a Mediterranean superpower, boasts more zest and intrigue than all the surrounding coastal resorts put together. During a holiday to Genoa you can explore its old town: a dense and fascinating warren of medieval alleyways home to large palazzi built in the sixteenth and seventeenth centuries by Genoa’s wealthy mercantile families and now transformed into museums and art galleries. You should seek out the Cattedrale di San Lorenzo, the Palazzo Ducale, and the Renaissance palaces of Via Garibaldi which contain the cream of Genoa’s art collections, as well as furniture and decor from the grandest days of the city’s past, when its ships sailed to all corners of the Mediterranean Sea. The Acquario di Genova is the city’s pride and joy, parked like a giant ocean liner on the waterfront, with seventy tanks ho…
Day 3Livorno(Florence), ItalyOct 31, 2026 • Arrives at: 8 am • Departs at: 6 pm
On the west coast of Tuscany lies the cosmopolitan port city of Livorno, an MSC Mediterranean Cruises destination. This Italian getaway is known for its historical architecture, sumptuous seafood, and checkboard waterside promenade. Livorno is the perfect launch pad for visiting Tuscany’s beautiful art cities, Florence and Pisa. What’s more, you’ll find great natural environments, like Macchia della Magona, spread across the region.
Day 4Marseille (Provence), FranceNov 1, 2026 • Arrives at: 9 am • Departs at: 6 pm
On the spectacular coastline of the French Riviera lies Marseille, an MSC Mediterranean Cruises destination. This atmospheric port city is known for its unique mix of grit and glamour, seen in its labyrinth of streets and historical architecture. Only a few miles from Marseille’s charismatic cafes and bustling Vieux Port, stunning cities are to be found. Visit Aix-en-Provence, birthplace of Cézanne, or take in the ancient beauty of Avignon.
Day 5Cruise returns to BarcelonaNov 2, 2026 • Arrives at: 7 am
One of the busiest cruise ports in the Mediterranean, the seaside city of Barcelona is known for its iconic architecture, colourful culture, and world-class drinking and dining. Explore Antoni Gaudí’s surreal Sagrada Família, the famous boulevard of the Ramblas, the medieval Barri Gótic, and the Museu Picasso. But there’s even more to discover in this sprawling Spanish city, an MSC Mediterranean Cruises destination: from hidden tapas bars and fabulous food markets to Europe’s biggest football stadium.
Cabin options
Compare the cabin types and onboard features shown for this sailing. Final price and availability are confirmed by our team when you inquire.
12 cabin grades listed for this sailing.
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