It’s easy to see why Barcelona is the most-visited city in Spain. As the capital of the country’s Catalonia region, this cityscape’s cultural mosaic pieces together a 2,000-year-old hodge-podge of sun-drenched beaches, cutting edge architecture and a world-renowned dining and drinking scene. Catalan architect Antoni Gaudi left his modernist handprint all over the city, while medieval treasures linger in historic Gothic Quarter squares. Get lost in the whimsical gardens of Park Guell or savour a chef-led Catalan cooking class. Browse art collections dedicated to Picasso and Miro – or ride a cable car to the top of Montjuic Hill, relishing citywide views along the way.

The Spanish island of Mallorca offers towering mountains and dramatic cliffs rising over clear, blue water – but its hidden gem is Palma de Mallorca (Majorca), the island's capital and largest city, where you'll find quaint historic streets, Gothic castles and gastronomic delights. Cruise to Palma de Mallorca and check out one-of-a-kind Palma Cathedral: The 14th-century Gothic spires of exterior contrast the modernist interior designed by in the early 1900s by Gaudi. See the circular courtyard and Arab-inspired arches of Castell de Bellver, and take in the fresh scent of the miles of pine forest that surround it. Or hire bikes and pedal east to Palma Beach, where you can soak in the sun on the white sands and clear waves.

Cartagena greets you with its ancient Mediterranean port on Spain's southeastern coast. Originally governed by the Carthaginians and subsequently by the Romans, Arabs and Castilians, this pedestrian-friendly city is a history buff's dream port. Visit the 2,000-year-old Roman Theatre and the attached museum, where you'll find an ancient altar to Jupiter and a statue of Apollo. Then, check out the late 19th-century modernist architecture of Cartagena's historic center. Cruises to Cartagena, Spain allow you to stroll down blue-marble-tiled pedestrian-only Calle Mayor. Or take the 30-minute drive to the Batteria de Castillitos, a medieval-style fortress situated among the picturesque mountain landscape.

The hub of Spain's southern Costa del Sol, Málaga is the picture of paradise. Scale the hilltop to dramatic La Alcazaba, the sandy-colored Moorish fortress dating back to the 11th century that overlooks this ancient seaside city. Sun yourself on the idyllic beaches of Caleta and Malagueta, taking in views of the mountains across the bay. See the eccentric works of modernist master Pablo Picasso, the city's most famous native son, at the Picasso Museum. Cruise to Málaga and immerse yourself in baroque and renaissance architecture at Málaga Cathedral, with its elaborate arches and stone reliefs depicting the saints, or turn the clock back to the first century A.D. at the ruins of the Roman Theatre.

Tangier, a Moroccan port on the Strait of Gibraltar, has been a strategic gateway between Africa and Europe since Phoenician times. Its whitewashed hillside medina is home to the Dar el Makhzen, a palace of the sultans that's now a museum of Moroccan artifacts. The American Legation Museum, also in the medina, documents early diplomatic relations between the U.S. and Morocco in an 1821 Moorish-style former consulate