15 Night Panama Canal Eastward Cruise

Bordered by the Anza-Borrego Desert, the Laguna Mountains, and the Pacific Ocean, San Diego is blessed with a year-round Mediterranean climate, which only adds to the attraction of its 70 miles of beaches. To learn more about this exciting port, please refer to our Port Explorer guide.

Puerto Vallarta – or simply Vallarta, as the locals call it – is a romantic's dream, with its cobblestoned lanes, beachfront eateries and an old city centre filled to the brim with charming boutiques. Jump onboard a Puerto Vallarta cruise and head to the shimmering waters of Yelapa beach for a dream-like escapade, or pop into Cafe des Artistes for a romantic meal in a candlelit garden. Then check out the landmark Los Arcos, a set of Roman-style arches by the waterfront, for a perfect photo of Vallarta's official symbol. For a break from the city life, head to Jardin Botanico Vallarta and enjoy the delightful scents of orchids and bromeliads and the refreshing waters of a boulder-filled river.

Puerto Quetzal is the ideal starting point to discover some of Guatemala's most iconic attractions. After a short ride outside of this port city, roam the Spanish Colonial streets of Antigua, a UNESCO World Heritage Site, with the colossal Volcan de Agua in the background. Cruise to Puerto Quetzal and learn how to weave using the back-strap loom technique or how to grind coffee by hand from the Maya women of San Antonio Aguascalientes. Then, reach Guatemela's highlands, and get happily lost in the town of Panajachel, with its pastel-coloured houses that face idyllic Lake Atitlan.

Situated on the long Nicoya Peninsula, Puntarenas is a great jumping-off point for the eco-adventures that have made Costa Rica famous. Trek lush rainforests in San Luis Park. Discover tropical flora and fauna in Pos Volcano National Park, and shower under Costa Rica's tallest waterfall at Pura Vida Gardens and Waterfalls. Looking for oceanside adventure? Take the short drive from Puntarenas to the Nicoya Peninsula, where there's a wide array of beaches – relax on family-friendly Playa Guiones, or check out dramatic Playa Ostional, with its volcanic black sands and vibrant sea turtle population. Puntarenas cruises give you access to Playa Tamarindo, where you can find some of the best surf and food in the country.

A voyage through the Panama Canal is filled with views of lush terrain and calm waters. This marvellous achievement of modernity is best witnessed from the bow of the ship, where you'll see the revolutionary mechanism of the canal at work when it elevates the vessel up 26 metres. The ship reaches the canal's higher elevation and is able to sail swiftly through its tranquil waters. As you make your way between the Pacific and Atlantic Oceans with your Panama Canal cruise, you'll pass by Soberania National Park, a lush region of protected rainforest – you may even spot one of the many species of rare birds that inhabit the forest.

Cartagena de Indias boasts romantic colonial architecture and a Caribbean coast glittering in shades of bright white and aquamarine. Saunter through the leafy Plaza de Bolivar, photographing multicolored streets like Calle Segunda de Badillo. Cruise to Cartagena to dance to the beat of merengue, salsa and Colombia's very own cumbia at places like Bazurto Social Club. Discover Proclamation Square, where the town people gathered in 1811 in support of the declaration of independence from Spain, and walk the 16th-century fortifications of Castillo San Felipe de Barajas. Enjoy Cartagena's natural grandeur on its many beaches, like Bocagrande, Playa Blanca and placid Rosario Islands National Park, just 45 minutes away from the city.

Grand Cayman is where the high life meets island life. This international banking haven is as much known for award-winning beaches as for the flocks of celebrities and high rollers that frequent them. You can sip Cayman Mama’s while rubbing shoulders with the global glitterati. During your Grand Cayman cruise, you can snorkel with stingrays in Stingray City. Treat your inner foodie at eateries established by acclaimed top chefs like Michael Schwartz, or chow down on conch fritters by the seashore. You can even soak up some rays at one of the beaches voted best in the world, Seven Mile Beach. And do it all in the same day.

While in Tampa, be sure to stroll through the historic Ybor City, full of restaurants, shops and bars, visit the Busch Gardens theme park or explore the Salvador Dali Museum in St. Petersburg. This metropolis never stands still.