Piraeus has been the port for Athens since 482 BC. The busy harbor is filled with ferries and cruise ships making their way to the Greek Islands and other Mediterranean cities. The busy metropolis of Athens and its treasure trove of antiquities lie just a few miles from the port. Even as the reality of the modern city took hold, with its high-rise apartments, crowded sidewalks and bustling traffic, the beauty of the Acropolis, the outstanding museums, charming cafés, sidewalk markets and startling views come together in a cultural mosaic for all to enjoy.

Monemvasia was once on the Peloponnese mainland. Then an earthquake turned it into an island. It is now joined to the mainland by a narrow causeway that limits access, originally for reasons of defense. The tall, flat isle is completely honeycombed with nooks and grottoes, narrow alleys and rock-carved rooms. Clearly it was a formidable redoubt in times of attack, and earned its nickname the Gibraltar of the East. The upper town, long uninhabited, has narrow pathways leading to the Byzantine Aghia Sophia church, and remains of the medieval fortress and walls. In the lower town, look for the bell tower that leads you to Elkomenos Square, with its namesake medieval Elkomenos Christos church and a small museum.

This charming village of white houses climbing up the slopes is beautifully situated on the sparkling Gulf of Mirabello. The attractive Venetian harbor is surrounded by restaurants, outdoor cafes and clusters of shops selling everything from necessities to souvenirs. The ship docks in the center of town, and you are able to wander at will and enjoy the atmosphere of Crete's foremost resort.

The quintessential Greek island of Mykonos is marked by whitewashed houses, domed churches, imposing windmills, and a labyrinth of winding streets designed to disorient pirates. Everywhere there is a dash of bright, bold blue - doors, shutters and window frames, sea and sky. The harbor bustles with colorful fishing boats, vendors selling fish and locals gathered with visitors in the casual seaside cafes. The port even comes with two beloved mascots, the pelicans Petros and Irini.

A popular holiday and resort destination, Cesme is located on a promontory on the tip of a peninsula that carries the same name. The town itself is dominated by the medieval Cesme Castle, while the back streets invite a casual stroll with their old Ottoman and Greek houses that charm passers-by. South of the castle there is an Ottoman caravanserai built in 1528 that has since been transformed into a lovely boutique hotel, and check the Greek Orthodox church of Ayios Haralambos to see the current art exhibition. Along with the historical attractions, visitors will enjoy local pleasures, such as a dip in the thermal baths followed by the culinary delights of native fruits, artisan cheeses and local wines.

Kusadasi, which means "bird island," is set in a superb gulf known for its sparkling water, broad sandy beaches and large marina. The city has managed to retain a certain earthiness while doing a brisk trade in Turkish carpets and leather goods to visitors. The town's old quarter is a picturesque maze of winding streets and houses adorned with flowers and birdcages. In the center stands a 17th-century caravanserai, now converted into a hotel. The resort is also gateway to important sites of archaeological and religious interest.

Spanning Europe and Asia, exotic Istanbul is one of the world's most fascinating cities. Domes and minarets enhance the skyline. In the old Stamboul area, traces remain of every city built since the community was established over 600 years before Christ. Once Rome's eastern capital, Istanbul was also the center of the huge Ottoman Empire. Landmarks include Hagia Sophia, once Christendom's greatest church; the Blue Mosque with its striking Iznik tiles; Topkapi Palace, containing a sultan's ransom of treasures; Chora Church with its Byzantine mosaics; and the Grand Bazaar, the ultimate shopping experience.