Journey to the Amazon - Panama City to Panama City, 9 Mar 2027 (22 nights)


Cruise search
We are checking available sailings, ship details and guide prices for you.


Ask our cruise specialists about cruise line loyalty benefits, status match options, drinks packages, gratuities and any current offers available on this sailing.
Sail with confidence
We explain the relevant financial protection before you book.
Always here to help
When plans change, your cruise specialists are here to help.
Carefully selected cruises
From short breaks to big adventures, we help narrow down the right sailing.
Cruise summary
Gallery

Onboard spaces
1 of 13 onboard highlights
Your itinerary
Port descriptions and imagery are shown where available for each day or port.
The Panama Canal is an artificial 82 km waterway in Panama that connects the Atlantic Ocean with the Pacific Ocean. The canal cuts across the Isthmus of Panama and is a conduit for maritime trade
While the city exhibits beautiful examples of both Dutch and Spanish architecture, it is now a Dutch city, taking its name from the Dutch royal house of Orange, and became the capital Aruba in 1979. When not heading for the famed beaches, the first spot most visitors enjoy is Wilhelmina Park, a lovely tropical garden by the waterfront, great for catching the Caribbean breezes. From here, travel on to the Archaeological Museum of Aruba or the Numismatic Museum of Aruba. The first offers an historical perspective; the latter, a fascinating display of coins from over 400 countries. Fort Zoutman (1796) is the oldest example of Dutch architecture on the island. In 1867, Willem III tower was added. Not only an excellent vantage point for photos, the fort also hosts music festivals and craft fairs.
Discover colorful Port of Spain with its rich multicultural heritage, skyscrapers, lush gardens, and early 20th Century mansions. Explore The Savannah, a vast 260-acre park and its orchid house. Indulge in a chilled fresh coconut from one of the park’s vendors. Visit the National Museum and Art Gallery, The Red House and The Magnificent Seven, a row of beautifully restored mansions dating from the Colonial era. Admire the clock tower in the Queen’s Royal College. Frederick St. offers fabulous restaurants, galleries and world-class shopping. Look for local artwork, fine clothing and other unique souvenirs. Enjoy fresh seafood, roti or callaloo while moving to the rhythm of Calypso music in this dynamic setting.
Please be advised that the ship stops in Macapa only to clear customs, and guests may not disembark. Please be advised that due to the under-developed nature of this destination, organized tours are not available.
Manaus, the “Paris of the Jungle,” is the capital of Brazil’s state of Amazonas. The former river village rests along the left bank of the Rio Negro, which merges with the mighty Amazon. Carved from the dense jungle by rubber barons in the 19th century, Manaus has become an ideal starting or ending point for visitors to the mid-Amazon region. Riverboats can be taken through the myriad of tributaries, estuaries and small creeks, where the richest wildlife can be seen. Attractions include the stunning Renaissance-style Opera House and the Customs House, prefabricated in Liverpool England complete with clock tower and known as “Little Big Ben.”
Manaus, the “Paris of the Jungle,” is the capital of Brazil’s state of Amazonas. The former river village rests along the left bank of the Rio Negro, which merges with the mighty Amazon. Carved from the dense jungle by rubber barons in the 19th century, Manaus has become an ideal starting or ending point for visitors to the mid-Amazon region. Riverboats can be taken through the myriad of tributaries, estuaries and small creeks, where the richest wildlife can be seen. Attractions include the stunning Renaissance-style Opera House and the Customs House, prefabricated in Liverpool England complete with clock tower and known as “Little Big Ben.”
We travel to experience life beyond the ordinary. Nestled on a 400 ft hill overlooking the Amazon, Boca Da Valeria is an Indian village located between Parintins and Santarem. This is an opportunity for you to wander at leisure through the small settlement or simply relax on board and take in up-close views of the rich equatorial vegetation from the ship. Ashore, you will find log canoes, grass huts, and a life of hunting and fishing unchanged since the time of the early explorers. Please be advised that due to the under-developed nature of this destination, organized tours are not available.
Twenty-five miles from the city of Santarém in Brazil is the Amazon River community of Alter Do Chao, named after the flat-topped hill that provides a natural backdrop. This small island is located on the Rio Tapajos, offering quaint cottages along the white-sand beaches lined with leafy palm trees. Thanks to its Indian handicrafts, lush vegetation, turquoise lagoon and amazingly clear water, Alter Do Chão has become a popular destination for travelers. Please be advised that due to the under-developed nature of this destination, organized tours are not available.
Please be advised that the ship stops in Macapa only to clear customs, and guests may not disembark. Please be advised that due to the under-developed nature of this destination, organized tours are not available.
Discover a touch of old Amsterdam transported to an island paradise. Pastel-hued buildings decorate the waterfront of this very Dutch Caribbean island. Don’t miss a visit to the colorful floating market, just a short walk from the Queen Emma Pontoon Bridge. A World Heritage site, the Punda district preserves hundreds of buildings as national monuments including Fort Amsterdam, the Governor’s Palace, Mikve Israel-Emanuel Synagogue, one of the first synagogue’s in the New World, and the waterfront’s colorful Penha building.
What's included
Fare overview
This sailing is shown as a cruise-only guide fare with Regent Seven Seas Cruises. The fare is linked to the ship, itinerary and cabin category you choose. Drinks packages, gratuities, Wi-Fi, flights, transfers and shore experiences are only treated as included where they are confirmed before booking.

Sailing aboard
Seven Seas Grandeur
Your ship
For more than thirty years, we have delivered unrivaled experiences throughout the world. All the while, we have been listening to our guests, evolving our services and continually refining each element of the Regent experience. Embrace the freedom enjoyed through the most all-inclusive luxury experience on the Seven Seas aboard a ship that elevates the pinnacle of ocean cruising to new heights. Inspired by the past and stunningly reimagined for the future, Seven Seas Grandeur™ will exemplify our heritage of perfection with unrivaled space, unparalleled service, exceptional cuisine and transformative experiences that will begin the moment you step aboard.
Onboard facilities

Wellness/Spa
Deck plans
Explore the ship deck by deck. Deck plans can change and should be checked before booking.
Deck 10

These facilities are available aboard the ship. Their deck locations can be confirmed before booking.
Match cabin grade codes and colours to the selected deck plan.
Choose your cabin
Compare live cabin grades, prices and availability for this sailing before continuing your booking.
Cabin guide
Next step
Continue to a separate page to review cruise extras and booking options around this sailing.
More sailings
Use horizontal scrolling, touch swipes, or the arrow keys to browse.
Important information
ATOL protected holidays
Where your booking includes flights, ATOL protection applies so your money and travel arrangements are financially protected.
Travel Trust Association
Book with confidence through a Travel Trust Association member, with customer money protected under approved trust arrangements.
Low deposit options
Secure selected sailings with flexible low deposit options, then spread the remaining balance before you travel.
Excellent customer service
Our cruise specialists are here before, during and after booking. Send an enquiry or call 0161 222 0822 for friendly support.
One Travel Club
Final price, cabin options and availability are checked before booking.
Clear price checks
Live prices and cabin options are checked before you continue.