Istanbul to Civitavecchia

Indulge your eyes and senses in this magnificent city astride two continents. Visit beautiful Topkapi Palace, the awesome Hagia Sophia and the impressive Blue Mosque. Cruise the Bosphorus to see the city and its surroundings from another perspective. Visit one of the many museums or stroll through the spice market and the famous Grand Bazaar.

Built on a promontory on the site of ancient Neapolis, Kavala offers fine beaches and numerous historic sites. A Byzantine castle lords over Kavala, and its 16th century aqueduct is still intact. The ruins of nearby Philippi include a Roman forum and a 5th century cathedral.

With a history spanning more than two millennia, Thessaloniki reigned alongside Constantinople as a capital of the Byzantine Empire. So numerous are the outstanding Paleochristian and Byzantine monuments that as a group they have been designated a UNESCO World Heritage Site. Don’t miss the ornate church and sacred crypt of St. Demetrius, the city’s martyred patron saint, or the palace complex of Galerius and the mosaics in the Rotunda. The Archaeological Museum holds even more ancient treasures.

Located at the foot of Mount Pelion, Volos wasn't founded until the mid-19th century, and its neoclassical architecture lends it a contemporary feel. The broad streets along the waterfront are excellent for strolling. Still, history hasn't been completely disregarded as the Archaeological Museum of Volos displays vast collections of ancient coins and glass vessels.

Meander through the ruins of ancient Ephesus and marvel at the famed Library of Celsus, the huge amphitheater, the marble roads with their chariot marks, the amazing mosaic sidewalks and the superb, rarely opened Terrace Houses. Or journey to three monumental cities of antiquity - Priene, Miletus and Didyma - renowned for their majestic temples and impressive, beautifully preserved stadiums.

Enjoy a walking tour of the old fortified city and stand in awe of the impressive Grand Master's Palace. See where the Colossus of Rhodes once stood and savor the charm of this remarkable walled town. Or drive along the scenic coast to Lindos. Enjoy the whitewashed little town and climb to the ancient acropolis, its temples and wonderful views.

Visit the beautiful whitewashed hilltop towns of Oia and Fira and their breathtaking views of the caldera below. See the stunning artifacts in Fira's museum, including recent finds from the excavation of Akrotiri, thought by many to be the legendary city of Atlantis, or visit a winery. Stroll through the winding streets with fantastic views around every corner.

Discover the myriad of cultural layers of Malta, from its amazing prehistoric temples at Tarxien to beautiful walled medieval Mdina, nearby Rabat, and Marsaxlokk, a colorful fishing village. Admire the stunning scenery and wander through imposing churches and down the streets of fortified towns where the Knights of St. John once held sway.

Salerno is a port city southeast of Naples, in Italy. Atop Monte Bonadies, the centuries-old Arechi Castle has sea views, plus Museo Medievale del Castello, exhibiting medieval ceramics and coins. In town, built on the ruins of a Roman temple, is Salerno Cathedral. It has Byzantine bronze doors, a baroque crypt and a marble altar. The terraced Minerva’s Garden has been growing medicinal plants since the 14th century.

Travel to Rome and revel in the magnificent monuments, from the ancient Roman Forum and Coliseum to the splendor of St. Peter's Basilica with Michelangelo's Pietà and his breathtaking frescoes in the Sistine Chapel. Or enjoy a drive through the lush farmlands of the Roman countryside to lovely medieval Castelgandolfo.